After about 3 miles turn left onto Casino Center Drive and you are only moments away from a star-studded good time. Turn right onto Maryland Heights Expressway. From the South, take 364 west to exit 17. Make a right hand turn onto Casino Center Drive. To get there from I-70, take Maryland Heights Expressway South to Casino Center Drive. Nothing but fun here, twenty four hours a day, seven days a week. If you are thinking of a day trip, an over nighter, or an extended gambling vacation then Hollywood Casino St. Betting on sports futures, props and lay bets.